Nick and Nora head to Nick’s hometown of Sycamore Springs to spend some time with his parents. His father, a prominent local physician, was always a bit disappointed with Nick’s choice of profession in particular and his lifestyle in general. With Nick’s arrival however the towns folk, including several of the local criminal element, are convinced that he must be there on a case despite his protestations that he’s just there for rest and relaxation. When someone is shot dead on his doorstep however, Nick finds himself working on a case whether he wants to or not.
Comedy | Crime | Mystery | Drama | Family | Romance
| William Powell | … | Nick Charles | |
| Myrna Loy | … | Nora Charles | |
| Lucile Watson | … | Mrs. Charles | |
| Gloria DeHaven | … | Laura Ronson (as Gloria De Haven) | |
| Anne Revere | … | Crazy Mary | |
| Helen Vinson | … | Helena Draque | |
| Harry Davenport | … | Dr. Bertram Charles | |
| Leon Ames | … | Edgar Draque | |
| Donald Meek | … | Willie Crump | |
| Edward Brophy | … | Brogan | |
| Lloyd Corrigan | … | Dr. Bruce Clayworth | |
| Anita Sharp-Bolster | … | Hilda (as Anita Bolster) | |
| Ralph Brooks | … | Peter Berton | |
| Donald MacBride | … | Police Chief MacGregor | |
| Morris Ankrum | … | Willoughby |